It drives me bonkers when I highlight text to read (I don't highlight everything, but I do it unconciously). When I highlight the text in chrome, it feels like my vision suddendly dropped out and I need glasses.
Very true, on windows at least every single browser renders fonts however they feel like. I wish someone would stand up and propose a standard way to render fonts (yes, I know pages don't necessarily have to look exactly pixel perfect across browsers, but it would simplify the design process a lot)
There has been talks of directwrite coming to Chrome for nearly a year now. We have to suffer the poorly hinted fonts looking terrible for a while longer.