I took the plunge and tried inverted scroll. At first it seemed weird, but after a day or so it felt like the most natural thing ever (and I've been using Macs since 1984). Now I find it difficult to go back to 'wrong way' scrolling.
I never got used to that, it seemed totally backwards to me. I can deal with it on a screen where my finger is (almost) physically attached to what I'm scrolling, but not on a detached mouse/trackpad and display.
I actually got used to it fairly quickly. After a day or two I instinctively used reverse (or "natural") scrolling, and I can switch back pretty easily when I'm using other people's computers. It does seem like almost no one else switched though.
I didn't just get used to the inverted scrolling, I fell in love with it. I think it makes perfect sense, and fells more "connected" with what I'm doing.
Loved that feature, it feels so much more natural. It was only a problem when I had to use a windows computer for like 5 minutes and everything was inverted again.
Yeah, that is how I felt at first as well. But I regularly use a Windows VM / Remote Desktop Client for Windows on my Mac, so I've gotten used to scrolling one way in the VM window or the RDC, and the other way outside it in the rest of my Mac.
Now, for better or worse, I have no problems switching my scrolling when I'm using someone's Windows computer.
My work computer is windows, and it was driving me nuts to have to reverse scroll... I found that I could invert scrolling on windows with the AutoHotKey app. Works pretty well.
This is why I try not to overtweak my computer. Sure I could rice the whole thing out, but then I'm useless on any other machine. I try to strike a happy medium where I'm reasonably productive but can still use another computer when I have to.
I dunno, I have tried it, and it was ok after a bit on the touchpad.
Then I plugged in a mouse. Did not work at all. I could not use it like that. So now I have scroll reverser[1] to scroll that way with just the trackpad. But really, I was flipping back and forth with the settings (there was something weird with the back/forward swipes for browsers) I don't even know which way it is right now. But it doesn't matter, as soon as I start moving it I can get feedback and do it correctly.
So I can get used to having it flipped on me rather quickly. I might make some false starts.
I'm completely sold on inverted scroll. 100%. It maps to touch interfaces and touch pads, it's "moving content" instead of moving that little (mostly invisible in Mountain Lion) progress bar, and the "moving content" concept fits extremely well with smooth deceleration - it always slides to a stop at the same distance after you've gone the same speed. The scroll bar becomes a progress bar and almost nothing else.
Innovation takes getting used to, evolution doesn't.