Using Emacs is not going to help you to avoid supply chain attacks per se. What it might do, however, is give you unparalleled power to inspect your environment - calls and source. If you run untrusted code you are exposed, and thats that. Development tools should assume that you, a programmer, know what you are programming.
Emacs and lisp is focused on providing power, not security. These often do not go hand in hand.
The entire point of this thread is how a chain of trust should be maintained. "Don't run untrusted code" is skipping from the question straight to a hypothetical world where an answer has already been established.
Emacs and lisp is focused on providing power, not security. These often do not go hand in hand.