For me hitting the ordinary control key is even more comfortable than hitting the caps-lock key. That's because to hit the caps-lock key I have to lift my little finger and move it to the left, while to hit the control key I only have to press down with the part of my palm that's directly below my little finger (and directly above the control key).
Since I learned Vim with the normal Escape key location and find it easier to hit than the normal Ctrl keys, I turn caps into another Ctrl. Plus, everything has Ctrl key shortcuts.