Peripheral neuropathy is the symptom, not the underlying issue. Zyrtec is popular among people who frequently sneeze but it's probably not what you're looking for if you're ingesting so much of a substance that it makes you sneeze uncontrollably.
Do you really want to be the person who has to explain to the doctor that you have no feeling in your hands because you're taking so much B6 every day for a bit of anxiety relief that it fried your nerves, but you thought that you could just cancel it out by taking a ridiculous amount of B1? Especially when there's so much else that can treat anxiety, including well-studied and benign things like lavender oil?
Do you really want to be the person who has to explain to the doctor that you have no feeling in your hands because you're taking so much B6 every day for a bit of anxiety relief that it fried your nerves, but you thought that you could just cancel it out by taking a ridiculous amount of B1? Especially when there's so much else that can treat anxiety, including well-studied and benign things like lavender oil?