People have taken them before. There were tests. A relative of mine was in one. Furthermore, the media doesn't certify which vaccines are safe. There are various governmental agencies in different countries for that.
Edmund Hoyle wrote a set of rules for the card game whist. His name was used in subsequent collections of rules for all sort of games. "According to Hoyle" has become idiomatic for "according to the rules."
Thank you. I've managed to go forty years without hearing that one. Now that I know the next level meaning, I'm still confused about what is being referenced.