A recent MedCram video on COVID-19 and lung function[0] mentioned the technique, and how he hopes it is used to figure out the lung failure modes for this disease. The lungs are very complex systems and the video goes through three possible ways for lungs to fail. COVID-19 is so new, doctors don't have a good understanding of which failure (bottleneck) is killing people. The technique was invented in the 70s to be able to disentangle all the flow factors and pinpoint where the rate limited step is in real diseased lungs.